Comparison of CCN2 mRNA levels among different cancer tissues and their adjacent normal tissues revealed significantly higher CCN2 expression in five types of cancer (DLBC, GBM, LGG, PAAD, and THYM) and significantly lower expression in 11 types of cancer [ACC, BLCA, CESC, KICH, KIRC, KIRP, LUAD, LUSC, SKCM, esophageal carcinoma, and uterine carcinosarcoma (UCS)]. Here, CCN2 is linked to adrenal cortex carcinoma.