Oral intake of either PLN or traditional PPE demonstrated significant reductions of ulcer index, oxidant mediator MDA, inflammatory cytokines IL-2, IL-6, and TNF-α immune-expression in gastric mucosa accompanied with marked elevation of serum levels of TAC, IL-10 denoting alleviation of the stressful conditions of oxidation and inflammation. The gene discussed is IL2; the disease is ulcer disease.