ADRB2 and inflammatory bowel disease: Examples include drugs with mast cell stabilizing activity such as beta-2 adrenoceptor antagonists (Scola et al., 2004) or cromolyn sodium (Zhang et al., 2016; Han et al., 2016), other histamine antagonists (for example H1 and H4 types) (Okayama et al., 1994; Marone et al., 2003; Hogan et al., 2020), leukotriene antagonists and leukotriene receptor antagonists (Fidan and Aydogdu, 2020), anti-inflammatory agents such as those developed for inflammatory bowel diseases, and mast cell activation inhibitors (Castells and Butterfield, 2019; Theoharides et al., 2019).