For example, the ALS-implicated protein FUS contains three arginine/glycine-rich regions and its propensity to localize with stress granules can be modulated by conditional the overexpression of PRMT1 in HEK293 cells (Yamaguchi and Kitajo, 2012; Ozdilek et al., 2017). The gene discussed is FUS; the disease is amyotrophic lateral sclerosis.