Another study has even suggested that ALS-related protein C9orf72 and autophagy receptor p62 associate with stress granules harboring symmetrically dimethylated arginine motifs, and that symmetric dimethylation by PRMT5 drives the formation of a complex that eliminates stress granules by autophagy (Chitiprolu et al., 2018). The gene discussed is C9orf72; the disease is amyotrophic lateral sclerosis.