CD19 and diffuse large B-cell lymphoma: Remarkable results were achieved with CAR-modified T cells targeting CD19 in relapsed/refractory patients with diffuse large B cell lymphoma (DLBCL) [5] and pediatric B cell acute lymphoblastic leukemia (ALL) [6] (50–90% CR), which inspired development of CAR-T cellular therapy for other indications, such as AML.