NTRK2 and Anxiety: As such, the present null data on 5-HTT’s and TrkB receptors in female mice indicate that early-life SSRI exposure mediates divergent lasting changes in membrane bound receptors (5-HTT and TrkB) that are male22 but not female-specific (Figs. 5B, 6B); highlighting a long-term FLX-induced molecular signature between the sexes that results in anxiety-like behavior in both females and males.