Moreover, ectopic expression of E47 inhibited cell proliferation in adenocarcinoma A549 and H1299 cells, as evidenced by MTS assays and colony formation assays (Fig. 1C, D), while ectopic expression of E47 promoted cell proliferation in SCC H292, FaDu, and KYSE150 cells (Fig. 1E, F and Fig. S1B). This evidence concerns the gene TCF3 and adenocarcinoma.