We only identified motifs linked to TFs of the ZEB/SNAI family, which are known repressors in the neural crest lineage, including in melanomas (Supplemental Fig. S10) (Postigo and Dean 1999; Postigo et al. 1999; Peinado et al. 2007; Caramel et al. 2013; Denecker et al. 2014). The gene discussed is ZEB1; the disease is melanoma.