MAPT and Alzheimer disease: As our group previously demonstrated the presence of phosphorylated forms of α-synuclein in the pancreatic tissue of patients with synucleinopathies [39], as well as deposition of phosphorylated, truncated and oligomeric forms of tau and of Aβ in the pancreatic tissue of AD patients [40], we studied whether pancreatic β-cells of subjects with neurodegenerative diseases present cooccurrence of other misfolded proteins, as observed in the brain.