PDZK1IP1 and hepatocellular carcinoma: Consistent with the knockdown efficiency, reduction in MAP17 expression led to a significant decrease in glucose uptake (Fig. 2b), lactate production (Fig. 2c), extracellular acidification rate (Fig. 2d), and expression of glycolytic genes (Fig. 2e) in SMMC-7721 and HCC-LM3 cells.