MAP17 plays pleiotropic oncogenic roles in several human cancers, such as cell apoptosis [38], cell invasion [36], tumor growth [20, 39], chemotherapy sensitivity [35, 40, 41], epithelial mesenchymal transition (EMT) [42], stem cell-like properties [17], and inflammatory response [14, 18]. This evidence concerns the gene PDZK1IP1 and cancer.