However, prolonged FIPI incubation was correlated with slightly diminished basal pMAPKp42/44 levels in MDA-NEO breast cancer cells (Fig. 3c; Additional file 4: Fig. S3), which was also observed in MDA-HER2 cells (Fig. 3d; Additional file 4: Fig. S3). Here, ERBB2 is linked to breast carcinoma.