F2 and cirrhosis of liver: When compared to patients without liver cirrhosis (group C), patients with liver cirrhosis have significantly lower level of platelet (123.51 ± 66.66 vs. 239.60 ± 54.70*109/L,P = 4.34*10–40), hemoglobin (117.37 ± 14.91 vs. 124.97 ± 14.13 g/L,P = 3.7*10–7), prothrombin activity (96.79 ± 17.27 vs. 105.87 ± 11.14%, p = 1.0*10–5) and higher level of ALT(43.38 ± 60.49vs.20.74 ± 21.42 IU/L, p = 5.98*10–4), Total Bilirubin(20.35 ± 39.31 vs.11.00 ± 6.78 umol/L, p = 0.023), and creatinine (45.72 ± 7.49 vs.43.00 ± 6.65 umol/L, p = 2.25*10–3).