The patient under discussions was known to have a high risk CLL and exhibited a HCM diagnosed on the basis of a low level of PTH, a low normal level of 25 (OH) vitamin D and 1.25 (OH) vitamin D. A non-small cell carcinoma of lung with solitary bone metastasis in vertebra D7 was discovered after extensive investigation of his severe symptomatic hypercalcemia. This evidence concerns the gene PTH and Hypercalcemia.