Majority of MALT lymphomas are H. pylori infection positive and are quite sensitive to H. pylori eradication.[3,4] Genetic abnormalities are also common in MALT lymphomas and various chromosomal translocations have been described.[1] In gastric MALT lymphoma, t(11;18)/API2-MALT1 is the most frequent translocation detected in 20% of cases.[5] The API2-MALT1 positive MALT lymphomas are thought to be associated with absence of H. pylori infection. This evidence concerns the gene MALT1 and MALT lymphoma.