Because the case was considered resistant to H. pylori eradication and radiotherapy would be possible oncological treatment.[3,6] However, API2-MALT1 positive gastric MALT lymphomas can be also considered as favorable prognosis.[7,8] Since EUS suggested that the lesion was localized within the lamina propria mucosae, we performed ESD to achieve the en bloc resection of the lesion. The gene discussed is MALT1; the disease is MALT lymphoma.