Previous studies show that other cancer cell lines have comparable total formate efflux under normal cell culture conditions (i.e., without IFNγ): HCT116 = 14–16 fmol/cell/h, IMR90 = 10 fmol/cell/h, HEK293T = 9 fmol/cell/h, and A549 = 0.9 fmol/cell/h (Ducker et al., 2016; Meiser et al., 2016). This evidence concerns the gene IFNG and cancer.