A thorough review, including 57 articles, showed that the assertion of ARVC causality was initially derived from 3 publications from the same research group who first established linkage to chromosome 1q42-43, and subsequently to RYR2 in families with a phenotype called arrhythmogenic right ventricular dysplasia 2 described as CPVT with fibro-fatty replacement of the right ventricle.42 The clinical features described in these manuscripts reflect CPVT rather than ARVC with cases not meeting TFC. The gene discussed is RYR2; the disease is arrhythmogenic right ventricular cardiomyopathy.