Human induced pluripotent stem cell (hiPSC) lines derived from patients with Long-QT syndrome recapitulate the electrophysiological characteristics of this disease phenotype, and hiPSC-CMs showed altered glycosylation and trafficking of the potassium voltage-gated channel subfamily H, member 2 (KCNH2, HERG) [65, 68]. The gene discussed is KCNH2; the disease is Prolonged QT interval.