CRTC1 and neoplasm: We further implanted cell suspensions from salivary gland tumors arising from mCre-CM(+) mice s.c. in immunocompromised NOD.SCID mice and immunocompetent mCre-CM(–) mice that contained mCre but not the fusion transgene, and we observed tumor formation around 2 months (Figure 2H), indicating that these CRTC1-MAML2–induced tumor cells were fully transformed.