CRTC1 and tumor of salivary gland: Here, we developed a Cre-regulated CRTC1-MAML2 transgenic mouse model and showed that Cre-induced expression of the transgenic CRTC1-MAML2 fusion in salivary glands, either by crossing with MMTV-Cre mice or direct AAV-Cre transduction, resulted in the development of salivary gland tumors that closely mimicked the histological and molecular features of human MEC.