IL-8, also known as CXC motif ligand 8 (CXCL8), is a member of the CXC chemokine family that binds to target cells expressing the CXCR1 or CXCR2 receptors, thereby inducing chemotaxis of innate immune cells such as neutrophils and monocytes to sites of infection or injury [72], also contributing to angiogenesis and liver damage [73]. The gene discussed is CXCL8; the disease is infection.