In support of these findings the impairment of miRNA-dependent regulation was demonstrated in a variety of cancer cell models for various mRNAs including pro-oncogenic factors like LIN28B and HMGA2 (Busch et al., 2016), MITF (Goswami et al., 2015), MKI67 (Gutschner et al., 2014; Müller et al., 2020) and SRF (Müller et al., 2019). This evidence concerns the gene SRF and cancer.