Genetic variants of other genes, including GPD1L, SCN1B, SCN2B, SCN3B, RANGRF, SLMAP, KCNE3, KCNJ8, HCN4, KCNE5, KCND3, CACNA1C, CACNB2B, CACNA2D1, and TRPM4, may also underlie Brugada syndrome. The gene discussed is CACNA1C; the disease is Brugada syndrome.