SCN5A genetic alterations are present in 30% of all Brugada syndrome cases while the RYR2 genetic alterations are reported because of catecholaminergic polymorphic ventricular tachycardia, atrial fibrillation, and arrhythmogenic right ventricular cardiomyopathy. Here, RYR2 is linked to arrhythmogenic right ventricular cardiomyopathy.