BLM and cholangiocarcinoma: The results showed that various cell cycle-related KEGG pathways, such as the CELL CYCLE pathway, MISMATCH REPAIR pathway, and DNA REPLICATION pathway, were enriched in the high-expression group of BLM, indicating their contribution to CCA cell proliferation, and in vitro experiments results further confirmed the vital role of BLM in regulating the cell cycle of CCA.