TRAV1-2 and tuberculosis: Interestingly, Wong et al. (28) recently showed that TRAV1-2+ CD8 T cells (MAIT cells) in bronchoalveolar lavage (BAL) fluid had greater functional responses (TNF-α expression) to Mycobacterium smegmatis-infected APCs than peripheral blood MAIT cells in patients with untreated active TB.