PLA2R1 and membranous glomerulonephritis: There is currently ongoing trial in anti-PLA2R antibody-positive primary membranous nephropathy with an oral inhibitor of factor B iptacopan (LNP023) directed of the alternative complement pathway (NCT04154787) and one small phase 2 safety trial with anti-MASP2 monoclonal antibody narsoplimab (NCT02682407) inhibiting complement lectin pathway.