Figure 2A shows that the mPEG × HER2-modified Lipo-DiD on HER2+ the ovarian cancer cell surface was gradually decreased in a time-dependent manner after incubation with Lipo-DiD and no surface Lipo-DiD was detected in the mPEG × DNS-modified Lipo-DiD group (Fig. 2A). This evidence concerns the gene ERBB2 and ovarian cancer.