ERBB2 and neoplasm: In our previous study, Kao et al. suggested that the mPEG × HER2 can confer HER2 specificity to various mPEG-NPs (Lipo/IR780, FeOdots or Qdot565nm) by a simple mixing procedure25 and enhance their targeting ability to SK-BR-3 (HER2+) tumor cells, but not MDA-MB-468 (HER2−) tumor cells25.