The BsAb consists of one arm of Fab fragment against mPEG, which is lipid anchored on the surface of PLD5,16–18, and the other arm of single chain Fv (scFv) fragment against human epidermal growth factor receptor 2 (HER2) antigen, which is overexpressed on approximately 50% of ovarian cancer cells19–21. The gene discussed is ERBB2; the disease is ovarian cancer.