Among them, 13 genes (PRKACA, GSDMB, SCAF11, PJVK, CASP9, NOD1, PLCG1, NLRP1, GSDME, ELANE, TIRAP, CASP4, and GSDMD) were downregulated while 18 other genes (GPX4, NLRP7, NLRP2, CASP3, CASP6, TNF, IL1B, IL18, CASP8, NLRP6, GSDMA, GSDMC, PYCARD, CASP5, AIM2, NOD2, NLRC4, and NLRP3) were enriched in the tumour group. The gene discussed is GSDME; the disease is neoplasm.