Logit(P) = ln(p/1-p) = − 11.138 + 0.110*BMI + 0.234*PLD dose intensity + 0.018 * baseline ALT− 0.025* baseline 11 AST 1.225 * gallstone history + 0.681 * peripheral blood circulation + 1.073 * sweat excretion + 0.364 * with or without tumour + 0.680*HER-2 (where p represents the probability that MSHFS occurs, and 1-P represents the probability that MSHFS does not occur). The gene discussed is ERBB2; the disease is neoplasm.