IHC staining showed CBP protein to be significantly more expressed in breast carcinoma samples both the “invasive and the in situ components” samples (No. of positive cases/total: 217/252) compared with benign neoplasia samples (No. of positive cases/total: 31/42), and normal breast samples (No. of positive cases/total: 65/94) (p = 0.0001) (Fig. 6b). Here, CREBBP is linked to breast carcinoma.