PPARG and type 1 diabetes mellitus: T1D has been genetically associated with genes and signaling pathways, CTLA-4 [9], SUMO4 [10], CYP27B1 [11], PD-1 [12], KIAA0350 [13], tumor necrosis factor alpha signaling pathways [14], NLRP3 and NLRP1 inflammasomes signaling pathways [15], HIF-1/VEGF signaling pathway [16], l-arginine/NO pathway [17], and CaMKII/NF-κB/TGF-β1 and PPAR-γ signaling pathway [18].