As shown in Fig. 5 EGFR, GRIN2B, GJA1, CAP2, MIF, POLR2A, PRKACA, GABARAP, TLN1 and PXN achieved an AUC value of >0.982, demonstrating that these genes have high sensitivity and specificity for T1D diagnosis. The gene discussed is GRIN2B; the disease is type 1 diabetes mellitus.