Table 6 summarizes the target gene - miRNA regulatory network and target gene - TF regulatory network (target genes, miRNAs and TFs) that were identified in the T1D, which included GRIN2B, EGFR, DKK1, GJA1, RGS4, TLN1, IGF2R, POLR2A, ARHGAP1, HIP1, RGS4, EYA1, CCL19, PRL, PRKACA, GAB2, HIP1, PXN , RGL2, hsa-mir-4257, hsa-mir-564, hsa-mir-587, hsa-mir-941, hsa-mir-561-3p, hsa-mir-4300, hsa-mir-5694, hsa-mir-378b, hsa-mir-3918, hsa-mir-6719-3p, FOXD1, GATA2, FOXL1, TP53, JUND, STAT3, TFAP2A, KLF5, PPARG and HINFP. This evidence concerns the gene KLF5 and type 1 diabetes mellitus.