Table 6 summarizes the target gene - miRNA regulatory network and target gene - TF regulatory network (target genes, miRNAs and TFs) that were identified in the T1D, which included GRIN2B, EGFR, DKK1, GJA1, RGS4, TLN1, IGF2R, POLR2A, ARHGAP1, HIP1, RGS4, EYA1, CCL19, PRL, PRKACA, GAB2, HIP1, PXN , RGL2, hsa-mir-4257, hsa-mir-564, hsa-mir-587, hsa-mir-941, hsa-mir-561-3p, hsa-mir-4300, hsa-mir-5694, hsa-mir-378b, hsa-mir-3918, hsa-mir-6719-3p, FOXD1, GATA2, FOXL1, TP53, JUND, STAT3, TFAP2A, KLF5, PPARG and HINFP. The gene discussed is DKK1; the disease is type 1 diabetes mellitus.