In this study, a kainic acid (KA)-induced rat epilepsy model was used to mimic temporal lobe epilepsy, and the effects of SVHRP on the expression of molecules involved in epileptogenesis, including brain-derived neurotrophic factor (BDNF), neuropeptide Y (NPY), cAMP-response element binding protein (CREB), stromal interaction molecule (STIM), and calcium release-activated calcium channel protein 1 (ORAI1), were analyzed. The gene discussed is NPY; the disease is epilepsy.