Compared with noncirrhotic patients (liver stiffness <12 kPa), patients with presumed cirrhosis (liver stiffness ≥12 kPa had higher mean BMI (36.4 vs 31.2 years), AST (53 vs 26 U/L), ALT (59 vs 26 U/L), and alkaline phosphatase (116 vs 76 U/L) levels, higher APRI (0.894 vs 0.333), FIB-4 index (3.21 vs 1.88), NFS (1.580 vs 0.252), and were more likely to have diabetes (100% vs 51.6%), history of CVD (50% vs 12.8%), and MI (25% vs 4.3%) (all P < 0.05). The gene discussed is GPT; the disease is Cirrhosis.