ABCA1 and neoplasm: ABCG1 and ABCA1 have many similarities: both of them are regulated by LXR623 [51–54] and they have 101 common interacting chemicals (Figure S2), promoting the outflow of cholesterol from macrophages [51–54] and regulating the expression of macrophage inflammatory cytokines [28], etc. Hence, it may be possible to kill or suppress tumor cells by upregulating ABCG1 with LXR623.