However, findings have varied depending on the outcome measure used, with a recent meta-analysis showing that TSPO PET tracer binding is significantly elevated in patients with schizophrenia relative to controls when binding potential (BP) is used as an outcome measure, but when the tracer volume of distribution (VT) is used as the outcome measure, no significant differences are seen between patients with schizophrenia and healthy controls [26]. Here, TSPO is linked to schizophrenia.