COPB2 and hepatocellular carcinoma: Kaplan–Meier survival analysis (cases with a survival time of less than 30 days were not considered) indicated that HCC patients with high COPB2 expression had a more unfavorable prognosis than those with low COPB2 expression in both TCGA (Figure 2(g), high (n = 82) vs. low (n = 247), p < 0.0001) and ICGC cohorts (Figure 2(h), high (n = 58) vs. low (n = 172), p < 0.05).