In the univariate Cox analysis, shorter overall survival (OS) was found in those with higher expression of COPB2 (hazard ratio (HR) = 1.068, 95% confidence interval (CI): 1.037−1.099, p < 0.0001), higher T stage (HR = 1.665, 95% CI: 1.390−1.993, p < 0.0001), worse pathological stage (HR = 1.652, 95% CI: 1.349−2.024, p < 0.0001), and “with tumor” status (HR = 1.604, 95% CI: 1.116−2.306, p < 0.05) (Table 2). Here, COPB2 is linked to neoplasm.