HLA-C and COVID-19: Conversely, HLA-DRB1*15:01, HLA-DQB1*06:02, and HLA-B*27:07 alleles have been associated with Italian cases of an extremely severe or severe form of COVID-1924, and an increased frequency of HLA-C*07:29 and HLA-B*15:27 was detected in Chinese patients with COVID-19 in comparison to the Chinese control population25.