To better understand the impact of B7-H6 and others immune checkpoint molecules within Her2 positive cancer subtype, we sought correlations between clinical parameters and B7-H6 or PD-L1 expressions by tumor cells and TILs (Table 2), statistical analysis show only significant associations of B7-H6 or PD-L1 BCC expression with SBR grade (p = 0.025 and p = 0.035 respectively) but a limited significant association between TILs-B7-H6 status and lymph node invasion (p = 0.055). This evidence concerns the gene CD274 and cancer.