Moreover, expression of ferroptosis suppressor protein 1 (FSP1, formerly AIFM2), recently demonstrated to render cells more resistant to ferroptosis55,56, was elevated specifically in NSCLC (Supplementary Fig. 1d) cells suggesting that superior intracellular iron availability combined with low FSP1 expression may specifically prime SCLC for ferroptosis induction. This evidence concerns the gene AIFM2 and small cell lung carcinoma.