Moreover, additional cell death induced by erastin or two structurally distinct small molecule inhibitors against GPX4 (RSL357 and ML21058) could be rescued by co-incubation with Fer-1 (Fig. 2b, c; Supplementary Fig. 2a, b) in human SCLC cells, which contained some non-specific background cell death due to culture in suspension. The gene discussed is GPX4; the disease is small cell lung carcinoma.