LCN2 and Cachexia: NMR-based body composition analysis of the fat compartment demonstrated consistent increase in fat mass of Lcn2-KO tumor-bearing mice throughout the study, including early (day 4 post implantation), mid (day 8 post implantation), and late-stage (day 11 post implantation) cachexia for Lcn2-KO tumor-bearing mice (Fig. 3f–h).