No significant changes of ACADM, ACADL, and PNPLA2 expressions were observed when SLC25A20 was overexpressed in HLF cells or knocked-down in SNU-368 cells, indicating that the regulation of fatty-acid oxidation by SLC25A20 is independent of ACADM, ACADL, and PNPLA2 in HCC cells (Fig S4). This evidence concerns the gene PNPLA2 and hepatocellular carcinoma.