CDCA3 and cancer: We confirmed, via bioinformatics and luciferase reporter gene analyses, that hsa_circ_101555–miR-145-5p targets the oncogene CDCA3. Although several studies have implicated CDCA3 in the regulation of cancer development and progression48–50, to our knowledge, this is the first study to confirm CDCA3 expression in liver cancer tissues and report its positive correlation with hsa_circ_101555 expression and negative correlation with miR-145-5p expression.