We also observed that the promotive effects of ADCK1 on cell invasion and anchorage-independent growth depended on the Wnt/β-catenin signaling pathway (Fig. 6E, F), indicating that ADCK1 promoted the malignant phenotypes of colon cancer cells by activating the Wnt/β-catenin signaling pathway. This evidence concerns the gene ADCK1 and colonic neoplasm.