After addition of commercial fiber, compared with the LPS+AF group, the expression of ABC transporters, peptidases, and two-component system genes increased significantly (P < 0.05), and the expression of transporter genes tended to increase (P = 0.052), while the expression of genes for ribosomes, DNA repair and recombination proteins, pyrimidine metabolism, and amino acid-related enzymes decreased significantly (P < 0.05) (Fig. 6). Here, LAP3 is linked to atrial fibrillation.