Under immune stress, excessive secretion of inflammatory cytokines in the immune system, such as interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α), leads to damage of intestinal structure, digestion, absorption, and barrier function, thus increasing the risk of intestinal diseases such as intestinal inflammation and diarrhea (4, –, 8). The gene discussed is TNF; the disease is intestinal disorder.