Chung et al. selected 10 candidate hypermethylated genes from data collected from tumor tissue and tested these 10 genes in voided urine samples by quantitative methylation-specific RT-PCR and identified a multigene predictive model comprised of five target genes (MYO3A, CA10, NKX6-2, DBC1, and SOX11). Here, NKX6-2 is linked to neoplasm.