Walsh et al. (2013) [56] reported an association between expression of MUC2 (and also MUC5AC, MUC5B, and MUC6) and the presence of somatic BRAFV600E mutation, CIMP, MSI, MMR-deficiency and loss of CDX2 expression in a large series of CRC. The gene discussed is MUC6; the disease is hyperinsulinemic hypoglycemia, familial, 4.