TG and hypothyroidism: In conclusion, our data suggest that hypothyroidism might be a direct and/or indirectplayer in the pathogenesis of NASH/NAFLD, though prospective studies are warrantedin order to better define the role of hypothyroidism in the pathogenesis of NASH andits associated histological features, as new and promising molecules acting onmetabolic pathways regulated by thyroid hormones are on the way.