Similar observations were reported in human colorectal cancer cell lines, such as DLD‐1, Caco‐2, RKO, HT‐29, LoVo, SW480, and HCT116, where both FAM83D mRNA and protein level expression were found to be upregulated, especially in SW480 and HCT116 lines. Here, SACK1D is linked to colorectal cancer.