GLP‐1 receptor mediated improvements in bone strength and quality have also been demonstrated in various distinct forms of diabetes including insulin‐deficient type 1 diabetic mice (Mansur et al., 2015), insulin‐resistant high fat fed diabetic mice (Mansur et al., 2019a) as well as genetically induced type 2 diabetic animal models (Sun, Lu, et al., 2016). This evidence concerns the gene INS and type 2 diabetes mellitus.