The SOD1, SOD2, glutathione-disulfide reductase (GSR), catalase (CAT), and nuclear factor erythroid 2-related factor 2 (NFE2L2) genes are deregulated in bladder cancer (Wieczorek et al., 2017), oral squamous cell carcinoma (Pedro et al., 2018), breast cancer (Wolf et al., 2016), lung cancer (Zhang Y et al., 2016), MCF-7 cells (Shi et al., 2017), and HCC (Cheng et al., 2015; Guerriero et al., 2015; Wang et al., 2016a). This evidence concerns the gene GSR and oral cavity squamous cell carcinoma.