Comparisons of tumor vs. adjacent normal tissue stratified by CD73 expression revealed a significant correlation between CD73 levels and duration of biochemical recurrence-free survival: expression of CD73 above the cohort median in normal tumor-adjacent epithelium was shown to independently predict shorter biochemical recurrence-free survival (HR = 2.753, 95% CI = 1.483–5.109; p = 0.001). This evidence concerns the gene NT5E and neoplasm.