PTEN and hepatocellular carcinoma: Low expression of FTCD is correlated with poor prognosis (P < 0.001) in HCC as per the TCGA data [57]; meanwhile, FTCD overexpression suppressed the proliferation of BEL-7402 and SNU499 cells, resulting in increased PTEN protein and decreased PI3K, total Akt, and phosphorylated Akt protein in BEL-7402 and SNU499 cells.